Nine people were killed during a bible student session at the historically black church. Authorities say 21-year-old Dylann Roof admitted to shooting them, saying his intent was to "start a race war".
The killings have prompted a national discussion on race, leading presidential candidates from both parties to weigh in.
The attack has also had a profound effect on traditionally black churches in Chicago, which have long served as both the social and spiritual center of the community.
And on the South Side of Chicago, the Rainbow Push Coalition is holding its annual conference this weekend.
African American leaders from across the country vowed to combat racist attitudes through education and attempt to push new gun control measures.
There will be other events related to the Charleston killings held across the country and in Chicago this morning, where leaders of traditionally black churches say they'll pray for the victims.