There is one confirmed fatality in an accident along Interstate 70 in eastern Indiana.
The crash happened this morning on I-70, in Richmond, Indiana, which is east of Indianapolis in Wayne County, near the Ohio border.
Witnesses say the bus collided with a car.
All east bound lanes on I-70 are closed near the 149 mile marker and westbound lanes are restricted.
Details on the destination or origination of the Greyhound bus have not been released.
INDOT estimates the lanes will be closed for at least three hours.
This is a developing story. Please check back for updates.