The South Side Irish Parade kicks off Sunday at noon.
It runs on Western Avenue, starting at 103rd Street and going south to 115th Street.
Organizers say they plan to make it a lot more family-friendly this year, and promise to crack down on rowdy behavior.
Anyone caught drinking along the parade route could be fined up to $1000.
There will be street closures in the area beginning about 9 a.m. Sunday, according to the city; the road closures should last until about 3 p.m.
The parade website said there will be no parking on Western Avenue from 99th Street to 119th Street beginning at 6 a.m.; starting at 8 a.m., there will be no parking on the east side of Artesian Avenue from 103rd Street to 111th Street and on the west side of Claremont Avenue from 103rd Street to 107th Street.