A train carrying crude oil derailed and exploded in the Canadian town of Lac-Megantic in Quebec Saturday, killing at least one person.
Dozens of buildings are destroyed.
The rail company, Edward A. Burkhardt’s Rail World Inc., is based in Rosemont, just outside Chicago.
A spokesman for the company says the train was stopped when 73 cars uncoupled from the engine and rolled downhill into the town, before derailing.
Local media reported 100 people are missing, but police will not confirm that tally.
Lt. Guy Lapointe with Quebec Police reported they do expect the number of fatalities to rise.
The train was en route to Maine.
US firefighters are assisting Canadian crews.